Cloned (Comment) | Organism |
---|---|
functionally expressed in Escherichia coli as glutathione-S-transferase fusion protein, active enzyme | Homo sapiens |
functionally expressed in Escherichia coli as glutathione-S-transferase fusion protein, active enzyme | Candida albicans |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.376 | - |
N-acetyl-D-glucosamine | 37°C, pH 7.5 | Candida albicans | |
0.426 | - |
D-mannose | 37°C, pH 7.5 | Candida albicans | |
0.445 | - |
N-acetyl-D-glucosamine | 37°C, pH 7.5 | Homo sapiens | |
0.483 | - |
D-glucose | 37°C, pH 7.5 | Candida albicans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + N-acetyl-D-glucosamine | Homo sapiens | - |
ADP + N-acetyl-D-glucosamine 6-phosphate | - |
? | |
ATP + N-acetyl-D-glucosamine | Candida albicans | first reaction of inducible N-acetylglucosamine catabolic pathway, enables organism to grow on N-acetylglucosamine as sole carbon source | ADP + N-acetyl-D-glucosamine 6-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | - |
- |
- |
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
fusion protein from Escherichia coli | Homo sapiens |
fusion protein from Escherichia coli | Candida albicans |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-glucose | - |
Candida albicans | ADP + D-glucose 6-phosphate | - |
? | |
ATP + D-mannose | - |
Candida albicans | ? | - |
? | |
ATP + N-acetyl-D-glucosamine | - |
Homo sapiens | ADP + N-acetyl-D-glucosamine 6-phosphate | - |
? | |
ATP + N-acetyl-D-glucosamine | - |
Candida albicans | ADP + N-acetyl-D-glucosamine 6-phosphate | - |
? | |
ATP + N-acetyl-D-glucosamine | first reaction of inducible N-acetylglucosamine catabolic pathway, enables organism to grow on N-acetylglucosamine as sole carbon source | Candida albicans | ADP + N-acetyl-D-glucosamine 6-phosphate | - |
? | |
additional information | D-fructose, D-galactose, galactosamine, N-acetyl-D-galactosamine, mannosamine, N-acetyl-D-mannosamine do not serve as substrates | Homo sapiens | ? | - |
? | |
additional information | D-fructose, D-galactose, galactosamine, N-acetyl-D-galactosamine, mannosamine, N-acetyl-D-mannosamine do not serve as substrates | Candida albicans | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CaNag5p | part of cluster with 6 genes, product from gene CaNag5 | Candida albicans |
CaNag5p | - |
Candida albicans |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.03 | - |
N-acetyl-D-glucosamine | 37°C, pH 7.5 | Candida albicans | |
0.0325 | - |
N-acetyl-D-glucosamine | 37°C, pH 7.5 | Homo sapiens |