Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.40 extracted from

  • Wu, X.; Zhou, Y.; Zhang, K.; Liu, Q.; Guo, D.
    Isoform-specific interaction of pyruvate kinase with hepatitis C virus NS5B (2008), FEBS Lett., 582, 2155-2160.
    View publication on PubMed

Application

Application Comment Organism
medicine specific downregulation of M2-type pyruvate kinase by shRNA inhibits the replication of hepatitis C virus in hepatitis C virus replicon 9B cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information specific downregulation of M2-type pyruvate kinase by shRNA inhibits the replication of hepatitis C virus in hepatitis C virus replicon 9B cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P14618 isoform M2
-

Subunits

Subunits Comment Organism
More the hepatitis C virus RNA-dependent RNA polymerase interacts with M2-type pyruvate kinase, but not with L-type pyruvate kinase Homo sapiens