KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.05 | - |
Co-adenosine 5'-O-(2-thio-(R)-triphosphate) | pH 8.0 | Sus scrofa | |
0.058 | - |
Zn-adenosine 5'-O-(2-thio-(S)-triphosphate) | pH 8.0 | Sus scrofa | |
0.059 | - |
Cd-adenosine 5'-O-(2-thio-(R)-triphosphate) | pH 8.0 | Sus scrofa | |
0.075 | - |
Mn-adenosine 5'-O-(2-thio-(S)-triphosphate) | pH 8.0 | Sus scrofa | |
0.09 | - |
Co-adenosine 5'-O-(1-thio-(R)-triphosphate) | pH 8.0 | Sus scrofa | |
0.091 | - |
Ni-adenosine 5'-O-(2-thio-(R)-triphosphate) | pH 8.0 | Sus scrofa | |
0.1 | - |
Co-adenosine 5'-O-(2-thio-(S)-triphosphate) | pH 8.0 | Sus scrofa | |
0.12 | - |
Mg-adenosine 5'-O-(2-thio-(S)-triphosphate) | pH 8.0 | Sus scrofa | |
0.12 | - |
Zn-adenosine 5'-O-(2-thio-(R)-triphosphate) | pH 8.0 | Sus scrofa | |
0.14 | - |
Ca-adenosine 5'-O-(2-thio-(S)-triphosphate) | pH 8.0 | Sus scrofa | |
0.14 | - |
Ni-adenosine 5'-O-(2-thio-(S)-triphosphate) | pH 8.0 | Sus scrofa | |
0.16 | - |
Mg-adenosine 5'-O-(1-thio-(S)-triphosphate) | pH 8.0 | Sus scrofa | |
0.2 | - |
Co-adenosine 5'-O-(1-thio-(S)-triphosphate) | pH 8.0 | Sus scrofa | |
0.22 | - |
Cd-adenosine 5'-O-(1-thio-(R)-triphosphate) | pH 8.0 | Sus scrofa | |
0.28 | - |
Cd-adenosine 5'-O-(1-thio-(S)-triphosphate) | pH 8.0 | Sus scrofa | |
0.29 | - |
Mn-adenosine 5'-O-(2-thio-(R)-triphosphate) | pH 8.0 | Sus scrofa | |
0.46 | - |
Cd-adenosine 5'-O-(2-thio-(S)-triphosphate) | pH 8.0 | Sus scrofa | |
0.59 | - |
Mg-adenosine 5'-O-(2-thio-(R)-triphosphate) | pH 8.0 | Sus scrofa | |
0.6 | - |
Ca-adenosine 5'-O-(2-thio-(R)-triphosphate) | pH 8.0 | Sus scrofa | |
0.69 | - |
ATP | pH 8.0 | Sus scrofa | |
2.44 | - |
Mg-adenosine 5'-O-(1-thio-(R)-triphosphate) | pH 8.0 | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
adenosine 5'-O-(1-thio-triphosphate) + mevalonate | 40% of activity with ATP in the presence of 2 mM Mg2+ | Sus scrofa | adenosine 5'-O-(1-thio-diphosphate) + 5-phosphomevalonate | - |
? | |
adenosine 5'-O-(2-thio-triphosphate) + mevalonate | 54% of activity with ATP in the presence of 2 mM Mg2+ | Sus scrofa | adenosine 5'-O-(2-thio-diphosphate) + 5-phosphomevalonate | - |
? | |
adenosine 5'-O-(3-thio-triphosphate) + mevalonate | 4% of activity with ATP in the presence of 2 mM Mg2+ | Sus scrofa | adenosine 5'-O-(3-thio-diphosphate) + 5-phosphomevalonate | - |
? | |
ATP + mevalonate | ATPgammaS, ATPalphaS and ATPbetaS can act as substrates in presence of different activating divalent metal cations, in the presence of Mg2+ the R diastereomers of both ATPalphaS and ATPbetaS are the preferred substrates, in presence of Cd2+ the S diastereomers are more active | Sus scrofa | ADP + phosphomevalonate | - |
? | |
Ca-adenosine 5'-O-(2-thio-(R)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Ca-adenosine 5'-O-(2-thio-(S)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Cd-adenosine 5'-O-(1-thio-(R)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Cd-adenosine 5'-O-(1-thio-(S)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Cd-adenosine 5'-O-(2-thio-(R)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Cd-adenosine 5'-O-(2-thio-(S)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Co-adenosine 5'-O-(1-thio-(R)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Co-adenosine 5'-O-(1-thio-(S)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Co-adenosine 5'-O-(2-thio-(R)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Co-adenosine 5'-O-(2-thio-(S)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Mg-adenosine 5'-O-(1-thio-(R)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Mg-adenosine 5'-O-(1-thio-(S)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Mg-adenosine 5'-O-(2-thio-(R)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Mg-adenosine 5'-O-(2-thio-(S)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Mn-adenosine 5'-O-(2-thio-(R)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Mn-adenosine 5'-O-(2-thio-(S)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Ni-adenosine 5'-O-(2-thio-(R)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Ni-adenosine 5'-O-(2-thio-(S)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Zn-adenosine 5'-O-(2-thio-(R)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? | |
Zn-adenosine 5'-O-(2-thio-(S)-triphosphate) + (R)-mevalonate | - |
Sus scrofa | ? | - |
? |