Cloned (Comment) | Organism |
---|---|
- |
Bacillus anthracis |
expressed in Escherichia coli strain C41(DE3) | Bacillus anthracis |
Crystallization (Comment) | Organism |
---|---|
sitting drop vapour diffusion method using 24-26% ethylene glycol | Bacillus anthracis |
sitting-drop method. The crystal structure of Bacillus anthracis PanK is solved using multiwavelength anomalous dispersion data and refined at a resolution of 2.0 A | Bacillus anthracis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | the enzyme is not subject to feedback inhibition by CoASH | Bacillus anthracis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Bacillus anthracis | type III PanK in the spore-forming Bacillus anthracis plays an essential role in the novel thiol/disulfide redox biology of this category A biodefense pathogen | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus anthracis | - |
- |
- |
Bacillus anthracis | Q81VX4 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Bacillus anthracis |
Ni-NTA column chromatography | Bacillus anthracis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (R)-pantothenate | - |
Bacillus anthracis | ADP + (R)-4'-phosphopantothenate | - |
? | |
additional information | type III PanK in the spore-forming Bacillus anthracis plays an essential role in the novel thiol/disulfide redox biology of this category A biodefense pathogen | Bacillus anthracis | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | x-ray crystallography | Bacillus anthracis |
Synonyms | Comment | Organism |
---|---|---|
BaPanK | - |
Bacillus anthracis |
PanK | - |
Bacillus anthracis |
type III pantothenate kinase | - |
Bacillus anthracis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Bacillus anthracis |