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Literature summary for 2.7.1.33 extracted from

  • Halvorsen, O.; Skrede, S.
    Regulation of the biosynthesis of CoA at the level of pantothenate kinase (1982), Eur. J. Biochem., 124, 211-215.
    View publication on PubMed
Search for more literature for 2.7.1.33

Inhibitors

Inhibitors Comment Organism Structure
acetyl-CoA
-
 Rattus norvegicus
acyl-CoA-esters long-chain acyl-CoAs less efficient than short-chain ester Rattus norvegicus
Arachidonoyl-CoA
-
 Rattus norvegicus
CoA
-
 Rattus norvegicus
dephospho-CoA
-
 Rattus norvegicus
malonyl-CoA
-
 Rattus norvegicus
octanoyl-CoA
-
 Rattus norvegicus
oleoyl-CoA
-
 Rattus norvegicus
palmitoyl-CoA
-
 Rattus norvegicus
propionyl-CoA
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.016
-
 pantothenate pH 6.1, 37°C Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male Wistar
-
Rattus norvegicus
-
 on normal or clofibrate enriched diet
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0012
-
 pH 6.1, 37°C Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-pantothenate
-
 Rattus norvegicus ADP + D-4'-phosphopantothenate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.1
-
-
 Rattus norvegicus