Protein Variants | Comment | Organism |
---|---|---|
additional information | Aqp7-knockout mice | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
wild type and Aqp7 knockout male mice and mouse 3T3-L1 cell line | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipocyte | There is no difference in glycerol mRNA level between control 3T3-L1 adipocytes and 3T3-L1 Aqp7-RNAi transfected adipocytes, whereas a 4fold enzymatic activation of glycerol kinase is observable in Aqp7 knockout adipocytes (activity assay: 50 mM TrisHCl, pH 7.2, 5 mM ATP, 10 mM MgCl2, 100 mM KCl, 2.5 mM DTT, 4 mM glycerol, 500 microM 3H-glycerol, for 90 min at 37°C). | Mus musculus | - |
adipose | There is no difference in the mRNA levels and activities of adipose glycerol kinase between Aqp7-/- and Aqp7+/+ mice at 10 weeks of age. Adipose glycerol kinase activity of Aqp7-/- mice is significantly higher than that of wild type mice under the 12 h fasting state. The fat pads of the Aqp7-/- knockout mice are significantily larger than those of wild type mice at 20 weeks of age. | Mus musculus | - |
blood plasma | Aqp7-/- knockout mice have significantly lower plasma glycerol level under 12 h fasting conditions. | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
GYK | glycerol kinase | Mus musculus |