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Literature summary for 2.7.1.24 extracted from
- Biosynthesis of coenzyme A from phosphopantetheine from pantothenate (1954), J. Biol. Chem., 207, 767-773.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| cysteine | activation | Rattus norvegicus |  |
| cysteine | activation | Sus scrofa | |
| cysteine | activation | Columba sp. | |
| cysteine | in vitro | Rattus norvegicus | |
| cysteine | in vitro | Sus scrofa | |
| cysteine | in vitro | Columba sp. | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
| cytosol | - |
Sus scrofa | 5829 | - |
| cytosol | - |
Columba sp. | 5829 | - |
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
| mitochondrion | - |
Sus scrofa | 5739 | - |
| mitochondrion | - |
Columba sp. | 5739 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| H2S | activation, in vitro | Rattus norvegicus | |
| H2S | activation, in vitro | Sus scrofa | |
| H2S | activation, in vitro | Columba sp. | |
| Mg2+ | requirement | Rattus norvegicus | |
| Mg2+ | requirement | Sus scrofa | |
| Mg2+ | requirement | Columba sp. | |
| Mg2+ | 2 mM | Rattus norvegicus | |
| Mg2+ | 2 mM | Sus scrofa | |
| Mg2+ | 2 mM | Columba sp. | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Columba sp. | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
| liver | - |
Sus scrofa | - |
| liver | - |
Columba sp. | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| frozen, partially purified preparation, quite stable | Sus scrofa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + dephospho-CoA | - |
Rattus norvegicus | ADP + CoA | - |
? | |
| ATP + dephospho-CoA | - |
Sus scrofa | ADP + CoA | - |
? | |
| ATP + dephospho-CoA | - |
Columba sp. | ADP + CoA | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Rattus norvegicus |
| 37 | - |
assay at | Sus scrofa |
| 37 | - |
assay at | Columba sp. |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | - |
- |
Rattus norvegicus |
| 9 | - |
- |
Sus scrofa |
| 9 | - |
- |
Columba sp. |
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Release 2023.1 (January 2023)
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