Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Calmodulin | calmodulin-dependent enzyme is stimulated 3.5fold by addition of calmodulin in presence of Ca2+ | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Trifluoperazine | inhibits stimulation by calmodulin | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.6 | - |
NAD+ | - |
Homo sapiens | |
0.9 | - |
ATP | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | half-maximal activity at free calcium of approximately 0.0004 mM | Homo sapiens | |
Mg2+ | activity is strictly dependent on Mg2+. Maximal activity above 5 mM | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
169000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O95544 | - |
- |
Purification (Comment) | Organism |
---|---|
partial | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neutrophil | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + NAD+ | - |
Homo sapiens | ADP + NADP+ | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 9.5 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens |