Cloned (Comment) | Organism |
---|---|
the region of human PI3K-C2alpha cDNA corresponding to residues 2-144 is cloned into the SmaI-ECoRI sites of pGEX-2T, the fusion protein is expressed in Escherichia coli BL21, transfection to COS cells | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
plasma membrane | colocalization of the enzyme with plasma membrane-coated pits in COS-cells | Homo sapiens | 5886 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the class II phosphoinositide 3-kinase C2.alpha. is activated by clathrin and regulates clathrin-mediated membrane trafficking | ? | - |
? | |
additional information | Homo sapiens PI3K-C2alpha | the class II phosphoinositide 3-kinase C2.alpha. is activated by clathrin and regulates clathrin-mediated membrane trafficking | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
PI3K-C2alpha | - |
Homo sapiens PI3K-C2alpha | - |
PI3K-C2alpha | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the class II phosphoinositide 3-kinase C2.alpha. is activated by clathrin and regulates clathrin-mediated membrane trafficking | Homo sapiens | ? | - |
? | |
additional information | the class II phosphoinositide 3-kinase C2.alpha. is activated by clathrin and regulates clathrin-mediated membrane trafficking | Homo sapiens PI3K-C2alpha | ? | - |
? |