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Literature summary for 2.7.1.153 extracted from
- Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers (2007), Proc. Natl. Acad. Sci. USA, 104, 7809-7814.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in HEK-293T cell | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | regulatory p85 and catalytic p110 subunits are present in equimolar amounts in mammalian cell lines and tissues. No evidence for free p85 or p110 subunits could be obtained. Cell lines contain 10,000-15,000 p85/p110 complexes per cell, with p110beta and p110delta being the most prevalent catalytic subunits in nonleukocytes and leukocytes, respectively | Mus musculus |
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Release 2023.1 (January 2023)
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