Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mammalia | the adaptor subunits of the class IA enzymes bind phosphorylated Tyr residues, thereby linking the phosphoinositide 3-kinases catalytic subunit to tyr kinase signalling pathways | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mammalia | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate | - |
Mammalia | ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate | - |
? | |
ATP + phosphatidylinositol | - |
Mammalia | ADP + phosphatidylinositol 3-phosphate | - |
? | |
ATP + phosphatidylinositol 4-phosphate | - |
Mammalia | ADP + phosphatidylinositol 4,5-diphosphate | - |
? | |
additional information | enzyme interacts with active, GTP-bound Ras | Mammalia | ? | - |
? | |
additional information | the adaptor subunits of the class IA enzymes bind phosphorylated Tyr residues, thereby linking the phosphoinositide 3-kinases catalytic subunit to tyr kinase signalling pathways | Mammalia | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | - |
Mammalia |