Inhibitors | Comment | Organism | Structure |
---|---|---|---|
LY294002 | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | embryonic | Rattus norvegicus | - |
neuron | primary, cortical | Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
PI-3-K | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | PI-3-K and the PI-3-K signaling pathway, besides the MAPK signaling pathway, are involved in the signaling mechanism underlying the neuroprotection of brain-derived neurotrophic factor against hypoxic insult, molecular mechanisms, overview. ERK but not PI-3-K pathway induce CREB phosphorylation | Rattus norvegicus |