Application | Comment | Organism |
---|---|---|
medicine | PI3K lipid kinase is an attractive target for the development of therapeutic agents to treat cancer and other related diseases | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
in complex with inhibitor E5E2, hanging drop vapour diffusion method, 100 mM Tris pH 7.2, 200 mM ammonium sulfate, 21% PEG 4000 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ead125 | - |
Homo sapiens | |
Ly-294002 | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidylinositol | - |
Homo sapiens | ADP + phosphatidylinositol 3-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
phosphatidyl-inositol-3-kinase | - |
Homo sapiens |
PI3Kgamma | p110gamma catalytic subunit | Homo sapiens |