Any feedback?
Literature summary for 2.7.1.11 extracted from
- Identification and characterization of 2-keto-3-deoxygluconate kinase and 2-keto-3-deoxygalactonate kinase in the haloarchaeon Haloferax volcanii (2014), FEMS Microbiol. Lett., 361, 76-83.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.3 | - |
ATP | at pH 8.0 and 42°C | Haloferax volcanii |  |
| 8.8 | - |
2-dehydro-3-deoxy-D-gluconate | at pH 8.0 and 42°C | Haloferax volcanii | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 35000 | - |
6 * 35000, SDS-PAGE | Haloferax volcanii |
| 38000 | - |
- |
Haloferax volcanii |
| 194000 | - |
gel filtration | Haloferax volcanii |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 2-dehydro-3-deoxy-D-gluconate | Haloferax volcanii | - |
ADP + 2-dehydro-3-deoxy-6-phospho-D-gluconate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Haloferax volcanii | - |
- |
- |
| Haloferax volcanii | D4GR05 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-NTA column chromatography and gel filtration | Haloferax volcanii |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 2-dehydro-3-deoxy-D-gluconate | - |
Haloferax volcanii | ADP + 2-dehydro-3-deoxy-6-phospho-D-gluconate | - |
? | |
| additional information | the enzyme does also use 2-dehydro-3-deoxy-D-galactonate as substrate | Haloferax volcanii | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homohexamer | 6 * 35000, SDS-PAGE | Haloferax volcanii |
| homohexamer | 6 * 38000, CTAB-PAGE | Haloferax volcanii |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 2-keto-3-deoxygluconate kinase | - |
Haloferax volcanii |
| HVO_A0328 | - |
Haloferax volcanii |
| KDG kinase | - |
Haloferax volcanii |
| KDGal kinase | - |
Haloferax volcanii |
| KDGK-1 | - |
Haloferax volcanii |
| KDGK-2 | - |
Haloferax volcanii |
kcat/KM [mM/s]
| kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 8 | - |
2-dehydro-3-deoxy-D-gluconate | at pH 8.0 and 42°C | Haloferax volcanii | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
