Activating Compound | Comment | Organism | Structure |
---|---|---|---|
D-fructose 2,6-bisphosphate | - |
Rattus norvegicus | |
D-fructose 2,6-bisphosphate | strong stimulation of mammary gland PFK, Kact: 0.00005 mM | Mus musculus | |
additional information | ascites tumor PFK is not activated by fructose-1,6-bisphosphate | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
phosphoenolpyruvate | inhibition of mammary gland PFK | Mus musculus | |
phosphoenolpyruvate | - |
Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
78700 | - |
x * 78700, L-type PFK, immunoblot | Mus musculus |
86200 | - |
x * 86200, M-type PFK, immunoblot | Mus musculus |
87500 | - |
x * 87500, c-type PFK, immunoblot | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Ehrlich ascites carcinoma cell | L- and C-type PFK isoenzymes, to a lesser amount M-type PFK | Mus musculus | - |
mammary gland | - |
Mus musculus | - |
mammary gland | - |
Rattus norvegicus | - |
Subunits | Comment | Organism |
---|---|---|
? | x * 78700, L-type PFK, immunoblot | Mus musculus |
? | x * 86200, M-type PFK, immunoblot | Mus musculus |
? | x * 87500, c-type PFK, immunoblot | Mus musculus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.83 | - |
phosphoenolpyruvate | pH 7.2, 25°C, mammary gland and ascites tumor PFK | Mus musculus |