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Literature summary for 2.7.1.11 extracted from

  • Wegener, G.; Schmidt, H.; Leech, A.R.; Newsholme, E.A.
    Antagonistic effects of hexose 1,6-bisphosphates and fructose 2,6-bisphosphate on the activity of 6-phosphofructokinase purified from honey-bee flight muscle (1986), Biochem. J., 236, 925-928.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.11

Inhibitors

Inhibitors Comment Organism Structure
ATP
-
 Apis mellifera
citrate cAMP, ADP or fructose 1,6-bisphosphate restore activity Apis mellifera
D-fructose 1,6-bisphosphate 0.02 mM, 50% inhibition in the presence of physiological concentrations of ATP, AMP, phosphate and fructose 6-phosphate Apis mellifera
D-Glucose 1,6-bisphosphate 0.08 mM, 50% inhibition in the presence of physiological concentrations of ATP, AMP, phosphate and fructose 6-phosphate, inhibition is relieved by 50% by 0.008 mM fructose 2,6-bisphosphate Apis mellifera

Metals/Ions

Metals/Ions Comment Organism Structure
K+
-
 Apis mellifera
Mg2+ required for activity Apis mellifera
Mg2+ MgATP is the active substrate Apis mellifera

Organism

Organism UniProt Comment Textmining
Apis mellifera
-
 honey bee, sp. carnica, collecting worker bees
-

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
 Apis mellifera
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
130
-
-
 Apis mellifera

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-fructose 6-phosphate
-
 Apis mellifera ADP + D-fructose 1,6-bisphosphate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Apis mellifera