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Literature summary for 2.7.1.1 extracted from

  • Kim, Y.; Heinzel, N.; Giese, J.; Koeber, J.; Melzer, M.; Rutten, T.; Von Wiren, N.; Sonnewald, U.; Hajirezaei, M.
    A dual role of tobacco hexokinase 1 in primary metabolism and sugar sensing (2013), Plant Cell Environ., 36, 1311-1327.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrial membrane
-
Nicotiana tabacum 31966
-

Organism

Organism UniProt Comment Textmining
Nicotiana tabacum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
Nicotiana tabacum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-glucose
-
Nicotiana tabacum ADP + D-glucose 6-phosphate
-
?

Synonyms

Synonyms Comment Organism
hexokinase 1
-
Nicotiana tabacum
NtHXK1
-
Nicotiana tabacum

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
assay at Nicotiana tabacum

General Information

General Information Comment Organism
malfunction after silencing NtHXK1 using RNAi plants show stunted growth and leaf chlorosis Nicotiana tabacum
malfunction overexpression of NtHXK1 results in elevated glucose phosphorylation activity in leaf extracts or chloroplasts. NtHXK1 is able to complement the glucose-insensitive Arabidopsis mutant gin2-1 suggesting that NtHXK1 can take over glucose sensing functions Nicotiana tabacum