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Literature summary for 2.7.1.1 extracted from

  • Lengsfeld, C.; Schoenert, S.; Dippel, R.; Boos, W.
    Glucose- and glucokinase-controlled mal gene expression in Escherichia coli (2009), J. Bacteriol., 191, 701-712.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Thermus thermophilus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.16
-
ATP
-
Thermus thermophilus

Organism

Organism UniProt Comment Textmining
Thermus thermophilus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-glucose
-
Thermus thermophilus ADP + D-glucose 6-phosphate
-
?
ATP + D-mannose
-
Thermus thermophilus ADP + D-mannose 6-phosphate
-
?

Subunits

Subunits Comment Organism
dimer or tetramer at ambient temperature the enzyme represents an equilibrium of dimeric and tetrameric forms Thermus thermophilus

Synonyms

Synonyms Comment Organism
glk
-
Thermus thermophilus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
70
-
-
Thermus thermophilus

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
37
-
the enzyme is still active at 37°C Thermus thermophilus

Cofactor

Cofactor Comment Organism Structure
ATP
-
Thermus thermophilus

General Information

General Information Comment Organism
physiological function overexpressed glucokinase due to its structural similarity with Mlc, the repressor of malT, binds to the glucose transporter (PtsG), releasing Mlc and thus increasing malT repression Thermus thermophilus