Activating Compound | Comment | Organism | Structure |
---|---|---|---|
(6-ethoxyquinazolin-4-yl)(1-methyl-1H-pyrazol-3-yl)amine | increases glucokinase activity at glucose concentrations up to approximately 20 mM | Homo sapiens | |
(6-ethoxyquinazolin-4-yl)pyridin-2-ylamine | increases glucokinase activity at glucose concentrations below approximately 7 mM | Homo sapiens | |
(6-isopropoxyquinazolin-4-yl)(1-methyl-1H-pyrazol-3-yl)amine | increases glucokinase activity at glucose concentrations up to approximately 20 mM | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
nickel and FLAG affinity column chromatography and gel filtration | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
pancreatic beta cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-glucose | - |
Homo sapiens | ADP + D-glucose 6-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glucokinase | - |
Homo sapiens |
hexokinase D | - |
Homo sapiens |
hexokinase IV | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |