Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.1 extracted from

  • Southworth, R.; Davey, K.A.; Warley, A.; Garlick, P.B.
    A reevaluation of the roles of hexokinase I and II in the heart (2007), Am. J. Physiol. Heart Circ. Physiol., 292, H378-H386.
    View publication on PubMed
Search for more literature for 2.7.1.1

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion oleate decreases hexokinase-mitochondrial binding and abolishes insulin-mediated translocation of HK I. Under basal conditions, the fraction of hexokinase I that is mitochondrially bound is 5times greater than for hexokinase II. Insulin and ischemia cause a fourfold increase in hexokinase II binding but only a doubling of hexokinase I binding Rattus norvegicus 5739
-
mitochondrion under basal conditions, the fraction of hexokinase I that is mitochondrially bound is 5times greater than for hexokinase II. Insulin and ischemia cause a fourfold increase in hexokinase II binding but only a doubling of hexokinase I binding Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus hexokinase I and hexokinase II are independently regulated, implying that they perform different roles in cardiac glucose regulation ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P05708
-
-
Rattus norvegicus P27881
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information hexokinase I and hexokinase II are independently regulated, implying that they perform different roles in cardiac glucose regulation Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
hexokinase type I
-
 Rattus norvegicus
hexokinase type II
-
 Rattus norvegicus
HK
-
 Rattus norvegicus
HK II
-
 Rattus norvegicus