Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | competitive versus ATP, inhibition mode, 91.3% decreased activity | Saccharomyces cerevisiae | |
AMP | 51.4% decreased activity | Saccharomyces cerevisiae | |
CoA | 54.1% decreased activity | Saccharomyces cerevisiae | |
D-glucose 1,6-diphosphate | 15.7% decreased activity | Saccharomyces cerevisiae | |
D-glucose 6-phosphate | 54.3% decreased activity | Saccharomyces cerevisiae | |
GDP | 31.3% decreased activity | Saccharomyces cerevisiae | |
additional information | multiplex inhibitor screening, mass spectrometry-based assay | Saccharomyces cerevisiae | |
oxidized glutathione | 82.9% decreased activity | Saccharomyces cerevisiae | |
reduced glutathione | 54.5% decreased activity | Saccharomyces cerevisiae | |
trehalose 6-phosphate | 90.9% decreased activity | Saccharomyces cerevisiae | |
UDP | 51.9% decreased activity | Saccharomyces cerevisiae | |
UDP-glucose | 62.5% decreased activity | Saccharomyces cerevisiae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics, mass spectrometry-based assay, overview, the Mg2+ concentration influence the kinetics | Saccharomyces cerevisiae | |
0.1 | - |
ATP | pH 7.5, 22°C | Saccharomyces cerevisiae | |
0.13 | - |
D-glucose | pH 7.5, 22°C | Saccharomyces cerevisiae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-fructose | Saccharomyces cerevisiae | - |
ADP + D-fructose 6-phosphate | - |
? | |
ATP + D-glucose | Saccharomyces cerevisiae | first step in the process of glycolysis | ADP + D-glucose 6-phosphate | - |
? | |
ATP + D-mannose | Saccharomyces cerevisiae | - |
ADP + D-mannose 6-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Saccharomyces cerevisiae | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Saccharomyces cerevisiae |
120 | - |
commercial preparation | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-fructose | - |
Saccharomyces cerevisiae | ADP + D-fructose 6-phosphate | - |
? | |
ATP + D-glucose | - |
Saccharomyces cerevisiae | ADP + D-glucose 6-phosphate | - |
? | |
ATP + D-glucose | first step in the process of glycolysis | Saccharomyces cerevisiae | ADP + D-glucose 6-phosphate | - |
? | |
ATP + D-mannose | - |
Saccharomyces cerevisiae | ADP + D-mannose 6-phosphate | - |
? | |
additional information | relatively nonspecific enzyme | Saccharomyces cerevisiae | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ATP-D-hexose-6-phosphotransferase | - |
Saccharomyces cerevisiae |
HK | - |
Saccharomyces cerevisiae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
22 | - |
assay at room temperature | Saccharomyces cerevisiae |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.06 | - |
D-glucose | pH 7.5, 22°C, soluble enzyme | Saccharomyces cerevisiae | |
1.67 | - |
D-glucose | pH 7.5, 22°C, immobilized enzyme | Saccharomyces cerevisiae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Saccharomyces cerevisiae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Saccharomyces cerevisiae |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.122 | - |
ADP | pH 7.5, 22°C, versus ATP, dependennt on Mg2+ concentration | Saccharomyces cerevisiae |