Cloned (Comment) | Organism |
---|---|
the gene for SgcD is cloned into pET-30 Xa/LIC and expressed in Escherichia coli | Streptomyces globisporus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | SgcD activity is depended on the inclusion of Mg2+ | Streptomyces globisporus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
58500 | - |
x * 58500, SDS-PAGE | Streptomyces globisporus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
chorismate + L-glutamine | Streptomyces globisporus | the net conversion of chorismate to 3-enolpyruvoylanthranilate by the tandem action of SgcD and SgcG establishes a new branching point in chorismate metabolism leading to synthesis of C-1027, an enediyne antitumor antibiotic | (2S)-2-amino-4-deoxychorismate + L-glutamate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces globisporus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Streptomyces globisporus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
chorismate + L-glutamine | - |
Streptomyces globisporus | (2S)-2-amino-4-deoxychorismate + L-glutamate | - |
? | |
chorismate + L-glutamine | the net conversion of chorismate to 3-enolpyruvoylanthranilate by the tandem action of SgcD and SgcG establishes a new branching point in chorismate metabolism leading to synthesis of C-1027, an enediyne antitumor antibiotic | Streptomyces globisporus | (2S)-2-amino-4-deoxychorismate + L-glutamate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 58500, SDS-PAGE | Streptomyces globisporus |
Synonyms | Comment | Organism |
---|---|---|
2-amino-2-deoxyisochorismate (ADIC) synthase | - |
Streptomyces globisporus |
2-amino-2-deoxyisochorismate synthase | - |
Streptomyces globisporus |
ADIC synthase | - |
Streptomyces globisporus |
SgcD | - |
Streptomyces globisporus |