Crystallization (Comment) | Organism |
---|---|
in complex with 3-indolepropionic acid or DL-indole-3-lactic acid, hanging drop vapor diffusion method, using 22% (w/v) PEG 4000, 0.2 M sodium acetate, 0.1 M Tris, pH 8.5 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3-indolepropionic acid | - |
Homo sapiens | |
DL-indole-3-lactic acid | - |
Homo sapiens | |
indole-3-acetic acid | - |
Homo sapiens | |
indole-3-pyruvic acid | - |
Homo sapiens | |
additional information | glycerol is not a functional inhibitor of KAT I | Homo sapiens | |
trans-3-indolacrylic acid | - |
Homo sapiens | |
Tris | - |
Homo sapiens | |
tryptophan | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q16773 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-kynurenine + 2-oxobutyrate | - |
Homo sapiens | kynurenic acid + 2-aminobutanoate + H2O | - |
? | |
additional information | 3-indolepropionic acid and DL-indole-3-lactic acid are no substrates of kynurenine aminotransferase I | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | x-ray crystallography | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
KAT I | - |
Homo sapiens |
kynurenine aminotransferase I | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Homo sapiens |