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Literature summary for 2.6.1.7 extracted from

  • Rejdak, R.; Rummelt, C.; Zrenner, E.; Grieb, P.; Zarnowski, T.; Okuno, E.; Schlotzer-Schrehardt, U.; Naumann, G.O.; Kruse, F.; Junemann, A.G.
    Immunohistochemical identification of kynurenine aminotransferases in corpora amylacea in the human retina and optic nerve (2007), Folia Neuropathol., 45, 66-71.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Homo sapiens Q16773
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Homo sapiens Q8N5Z0
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Source Tissue

Source Tissue Comment Organism Textmining
corpora amylacea in some parts, only faint expression of isoform KAT II, and occasionally no staining. No association of staining variability for KAT II and localization of Corpora amylacea Homo sapiens
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corpus amylaceum KAT I may be involved in mechanisms of retinal ageing and neurodegeneration leading to formation of corpora amylacea Homo sapiens
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corpus amylaceum KAT II may be involved in mechanisms of retinal ageing and neurodegeneration leading to formation of corpora amylacea Homo sapiens
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optic nerve
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Homo sapiens
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optic nerve expression of both isoforms KAT I and KAT II. KAT I immunoreactivity is more intense than KAT II, and its staining is more pronounced in the retrolaminar part of the optic nerve Homo sapiens
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retina KAT I is observed on Müller cell endfeet Homo sapiens
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retina KAT II is expressed in retinal ganglion cells Homo sapiens
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retina expression of both isoforms KAT I and KAT II. KAT I immunoreactivity is more intense than KAT II, and its staining is more pronounced in the retrolaminar part of the optic nerve. Isoform KAT I is observed on Mueller cell endfeet while KAT II is expressed in retinal ganglion cells Homo sapiens
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Synonyms

Synonyms Comment Organism
KAT I
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Homo sapiens
KAT II
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Homo sapiens