Inhibitors | Comment | Organism | Structure |
---|---|---|---|
glutamine | 0.08 mM; 50% inhibition of placental KAT I | Homo sapiens | |
L-phenylalanine | - |
Homo sapiens | |
L-tryptophan | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | KAT I | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-kynurenine + pyruvate | placental KAT I, higher activity than with 2-oxoglutarate | Homo sapiens | kynurenic acid + L-alanine + H2O | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.8 | - |
total placental KAT activity | Homo sapiens |
9.8 | - |
placental KAT I activity | Homo sapiens |