Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EGTA | strong inhibition at pH 6.8 and Ca2+ concentrations below 0.5 mM | Rattus norvegicus | |
additional information | not inhibited by EGTA; not inhibited by quinolinate | Rattus norvegicus | |
quinolinic acid | strong inhibition at pH 6.8 and Ca2+ concentrations below 0.5 mM | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
CaCl2 | approx. 4fold increase in activity at pH 6.4 | Rattus norvegicus | |
additional information | not activated by chloride salts of Mg2+, Mn2+, Na+, K+ or NH4+ | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Sprague-Dawley | - |
Rattus norvegicus Sprague-Dawley | - |
Sprague-Dawley | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-kynurenine + 2-oxoglutarate | - |
Rattus norvegicus | kynurenic acid + L-glutamate + H2O | - |
? | |
L-kynurenine + 2-oxoglutarate | - |
Rattus norvegicus Sprague-Dawley | kynurenic acid + L-glutamate + H2O | - |
? |