KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.6 | - |
L-kynurenine | pH 6.5, 37°C, enzyme from supernatant | Rattus norvegicus | |
2.5 | - |
L-kynurenine | pH 6.5, 37°C, mitochondrial enzyme | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | 10% of liver total activity at pH 6.5 | Rattus norvegicus | 5764 | - |
mitochondrion | - |
Rattus norvegicus | 5739 | - |
additional information | subcellular distribution | Rattus norvegicus | - |
- |
soluble | 12% of liver total activity at pH 6.5 | Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Donryu | - |
Rattus norvegicus Donryu | - |
Donryu | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-3-hydroxykynurenine + 2-oxoglutarate | - |
Rattus norvegicus | xanthurenic acid + L-glutamate | - |
? | |
L-3-hydroxykynurenine + 2-oxoglutarate | - |
Rattus norvegicus Donryu | xanthurenic acid + L-glutamate | - |
? | |
L-kynurenine + 2-oxoglutarate | - |
Rattus norvegicus | kynurenic acid + L-glutamate + H2O | - |
? | |
L-kynurenine + 2-oxoglutarate | - |
Rattus norvegicus Donryu | kynurenic acid + L-glutamate + H2O | - |
? | |
L-kynurenine + pyruvate | - |
Rattus norvegicus | kynurenic acid + L-alanine + H2O | - |
? | |
L-kynurenine + pyruvate | - |
Rattus norvegicus Donryu | kynurenic acid + L-alanine + H2O | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | 6.5 | - |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | 8.8 | maximal activity at pH 6.5, approx. half-maximal activity at pH 8.8 | Rattus norvegicus |