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Literature summary for 2.6.1.42 extracted from

  • Caballero, J.; Vergara-Jaque, A.; Fernandez, M.; Coll, D.
    Docking and quantitative structure-activity relationship studies for sulfonyl hydrazides as inhibitors of cytosolic human branched-chain amino acid aminotransferase (2009), Mol. Divers., 13, 493-500.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-isoleucine + 2-oxoglutarate Homo sapiens
-
3-methyl-2-oxopentanoate + L-glutamate
-
?
L-leucine + 2-oxoglutarate Homo sapiens
-
2-oxoisohexanoate + L-glutamate
-
?
L-valine + 2-oxoglutarate Homo sapiens
-
3-methyl-2-oxobutanoate + L-glutamate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P54687
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-isoleucine + 2-oxoglutarate
-
Homo sapiens 3-methyl-2-oxopentanoate + L-glutamate
-
?
L-leucine + 2-oxoglutarate
-
Homo sapiens 2-oxoisohexanoate + L-glutamate
-
?
L-valine + 2-oxoglutarate
-
Homo sapiens 3-methyl-2-oxobutanoate + L-glutamate
-
?

Synonyms

Synonyms Comment Organism
BCATc
-
Homo sapiens
branched-chain amino acid aminotransferase
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Homo sapiens