Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(Z)-4-amino-2-butenoic acid | - |
Homo sapiens | |
3-chloro-1-(4-hydroxyphenyl)propan-1-one | irreversible and potent inhibitor, about 30% residual activity at 0.06 mM, 2-oxoglutarate prevents the enzyme from inactivation | Homo sapiens | |
4-hydroxybenzaldehyde | competitive inhibitor of GABA transaminase | Homo sapiens | |
vigabatrin | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-aminobutanoate + 2-oxoglutarate | - |
Homo sapiens | 4-oxobutanoate + L-glutamate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GABA transaminase | - |
Homo sapiens |
GABA-T | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00399 | - |
- |
Homo sapiens | 3-chloro-1-(4-hydroxyphenyl)propan-1-one | |
0.0165 | - |
- |
Homo sapiens | 4-hydroxybenzaldehyde |