Literature summary for 2.6.1.1 extracted from

Hayashi, H.; Mizuguchi, H.; Miyahara, I.; Islam, M.M.; Ikushiro, H.; Nakajima, Y.; Hirotsu, K.; Kagamiyama, H.
Strain and catalysis in aspartate aminotransferase (2003), Biochim. Biophys. Acta, 1647, 103-109.

Search for more literature for 2.6.1.1

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-aspartate + 2-oxoglutarate	reaction mechanism, the strain (unfavourable interaction) of the distorted internal aldimine in the unliganded enzyme is crucial for catalysis. The true driving forces are the strain energy inherent to the respective intermediates. It is described how these strain energies are generated and are used for catalysis	Escherichia coli	oxaloacetate + L-glutamate	-	?

Synonyms

Synonyms	Comment	Organism
AAT	-	Escherichia coli
aspartate aminotransferase	-	Escherichia coli

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)