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Literature summary for 2.6.1.1 extracted from

  • Okada, M.; Ayabe, Y.
    Effects of aminoguanidine and pyridoxal phosphate on glycation reaction of aspartate aminotransferase and serum albumin (1995), J. Nutr. Sci. Vitaminol., 41, 43-50.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
aminoguanidine competes with the enzyme for pyridoxal 5'-phosphate, forms complexes with pyridoxal 5'-phosphate, 70% enzyme inhibition at 1 mM Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol cytosolic isoenzyme Rattus norvegicus 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-aspartate + 2-oxoglutarate Rattus norvegicus
-
 oxaloacetate + L-glutamate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male Wistar rats
-
Rattus norvegicus
-
 purified cytosolic isozyme
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-aspartate + 2-oxoglutarate
-
 Rattus norvegicus oxaloacetate + L-glutamate
-
 ?

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate a pyridoxal 5'-phosphate protein Rattus norvegicus