Any feedback?
Literature summary for 2.5.1.60 extracted from
- Rab-geranylgeranyl transferase regulates glucose-stimulated insulin secretion from pancreatic beta cells (2012), Islets, 4, 354-358.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | siRNA-mediated knockdown of alpha- or beta-subunits of the enzyme and Rab escort protein-1 markedley attenuates glucose-stimulated insulin secretion in INS-1 832/13 cells | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| INS-1 832/13 cell | expression of both alpha- and beta-subunit of enzyme as well as Rab escort protein-1 | Rattus norvegicus | - |
| pancreatic islet | expression of both alpha- and beta-subunit of enzyme as well as Rab escort protein-1 | Rattus norvegicus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Rab GGTase | - |
Rattus norvegicus |
| RGGT | - |
Rattus norvegicus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | siRNA-mediated knockdown of alpha- or beta-subunits of the enzyme and Rab escort protein-1 markedley attenuates glucose-stimulated insulin secretion in INS-1 832/13 cells | Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
