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Literature summary for 2.5.1.60 extracted from

  • Wojtas, M.; Swiezewski, S.; Sarnowski, T.J.; Plochocka, D.; Chelstowska, A.; Tolmachova, T.; Swiezewska, E.
    Cloning and characterization of Rab Escort Protein (REP) from Arabidopsis thaliana (2007), Cell Biol. Int., 31, 246-251.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
geranylgeranyl diphosphate + Rab protein Arabidopsis thaliana intracellular vesicular trafficking is regulated by Rab proteins, small GTPases that require posttranslational geranylgeranylation for biological activity, which is catalyzed by the enzyme, a Rab geranylgeranyl transferase together with the Rab escort protein, REP, overview S-geranylgeranyl-Rab protein + diphosphate
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?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
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-
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geranylgeranyl diphosphate + Rab protein
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Arabidopsis thaliana S-geranylgeranyl-Rab protein + diphosphate
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?
geranylgeranyl diphosphate + Rab protein intracellular vesicular trafficking is regulated by Rab proteins, small GTPases that require posttranslational geranylgeranylation for biological activity, which is catalyzed by the enzyme, a Rab geranylgeranyl transferase together with the Rab escort protein, REP, overview Arabidopsis thaliana S-geranylgeranyl-Rab protein + diphosphate
-
?

Synonyms

Synonyms Comment Organism
Rab geranylgeranyl transferase
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Arabidopsis thaliana
RabGGTase
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Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
additional information the enzyme is absolutely dependent on the Rab escort protein, REP, cloning and expression of His-tagged REP in Escherichia coli, and purification, overview Arabidopsis thaliana