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Literature summary for 2.5.1.6 extracted from

  • Vazquez-Chantada, M.; Ariz, U.; Varela-Rey, M.; Embade, N.; Martinez-Lopez, N.; Fernandez-Ramos, D.; Gomez-Santos, L.; Lamas, S.; Lu, S.C.; Martinez-Chantar, M.L.; Mato, J.M.
    Evidence for LKB1/AMP-activated protein kinase/endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation (2009), Hepatology, 49, 608-617.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
liver expression of isoform MAT1A in the adult liver. During hepatic de-differentiation, the switch between MAT1A and MAT2A coincides with an increase in HuR and AUF1 expression. S-adenosylmethionine treatment alters this homeostasis by shifting the balance of AUF1 and methyl-HuR/HuR. Similar temporal distribution and functional link between HuR, methyl-HuR, AUF1, and MAT1A and MAT2A during fetal liver development Homo sapiens
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