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Literature summary for 2.5.1.6 extracted from

  • Hacham, Y.; Song, L.; Schuster, G.; Amir, R.
    Lysine enhances methionine content by modulating the expression of S-adenosylmethionine synthase (2007), Plant J., 51, 850-861.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information lysine enhances methionine content by modulating the expression of S-adenosylmethionine synthase, overview Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information expression of dihydrodipicolinate synthase or co-expression of cystathionine gamma-synthase and dihydrodipicolinate synthase from Arabidopsis thaliana in tobacco leaves and seeds results in enhanced methionine levels, overview Nicotiana tabacum

Metals/Ions

Metals/Ions Comment Organism Structure
K+
-
Nicotiana tabacum
K+
-
Arabidopsis thaliana
Mg2+
-
Nicotiana tabacum
Mg2+
-
Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-methionine + H2O Arabidopsis thaliana aspartate family biosynthesis pathway and methionine metabolism, regulation, S-adenosyl-L-methionine activates threonine synthase expression and negatively regulates the transcript level of the cystathionine gamma-synthase, overview phosphate + diphosphate + S-adenosyl-L-methionine
-
?
ATP + L-methionine + H2O Nicotiana tabacum aspartate family biosynthesis pathway and methionine metabolism,regulation, S-adenosyl-L.methionine activates threonine synthase expression and negatively regulates the transcript level of the cystathionine gamma-synthase, overview phosphate + diphosphate + S-adenosyl-L-methionine
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-
Nicotiana tabacum
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
Nicotiana tabacum
-
seed
-
Nicotiana tabacum
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Nicotiana tabacum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-methionine + H2O
-
Nicotiana tabacum phosphate + diphosphate + S-adenosyl-L-methionine
-
?
ATP + L-methionine + H2O
-
Arabidopsis thaliana phosphate + diphosphate + S-adenosyl-L-methionine
-
?
ATP + L-methionine + H2O aspartate family biosynthesis pathway and methionine metabolism, regulation, S-adenosyl-L-methionine activates threonine synthase expression and negatively regulates the transcript level of the cystathionine gamma-synthase, overview Arabidopsis thaliana phosphate + diphosphate + S-adenosyl-L-methionine
-
?
ATP + L-methionine + H2O aspartate family biosynthesis pathway and methionine metabolism,regulation, S-adenosyl-L.methionine activates threonine synthase expression and negatively regulates the transcript level of the cystathionine gamma-synthase, overview Nicotiana tabacum phosphate + diphosphate + S-adenosyl-L-methionine
-
?

Synonyms

Synonyms Comment Organism
S-adenosylmethionine synthase
-
Nicotiana tabacum
S-adenosylmethionine synthase
-
Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
ATP
-
Nicotiana tabacum
ATP
-
Arabidopsis thaliana