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Literature summary for 2.5.1.6 extracted from

  • Lindermayr, C.; Saalbach, G.; Bahnweg, G.; Durner, J.
    Differential inhibition of Arabidopsis methionine adenosyltransferases by protein S-nitrosylation (2006), J. Biol. Chem., 281, 4285-4291.
    View publication on PubMed
Search for more literature for 2.5.1.6

Inhibitors

Inhibitors Comment Organism Structure
nitrosoglutathione reversibly inhibits the isozyme MAT1 via NO binding to Cys114, no inhibition of isozymes MAT2 and MAT3, molecular mechanism for S-nitrosylation of the enzyme Arabidopsis thaliana

Metals/Ions

Metals/Ions Comment Organism Structure
K+
-
 Arabidopsis thaliana
Mg2+
-
 Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-methionine + H2O Arabidopsis thaliana
-
 phosphate + diphosphate + S-adenosyl-L-methionine
-
 ?
additional information Arabidopsis thaliana protein S-nitrosylation by NO represents a redox-based regulation mechanism playing a pivotal role in plants, MAT catalyzes the synthesis of the ethylene precursor S-adenosylmethionine and NO influences ethylene production in plants, the enzyme probably mediates the cross-talk between ethylene and NO signaling, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
 isozymes MAT1, MAT2, and MAT3
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-methionine + H2O
-
 Arabidopsis thaliana phosphate + diphosphate + S-adenosyl-L-methionine
-
 ?
additional information protein S-nitrosylation by NO represents a redox-based regulation mechanism playing a pivotal role in plants, MAT catalyzes the synthesis of the ethylene precursor S-adenosylmethionine and NO influences ethylene production in plants, the enzyme probably mediates the cross-talk between ethylene and NO signaling, overview Arabidopsis thaliana ?
-
 ?

Synonyms

Synonyms Comment Organism
MAT
-
 Arabidopsis thaliana

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
35
-
 assay at Arabidopsis thaliana

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Arabidopsis thaliana