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Literature summary for 2.5.1.6 extracted from

  • Wang, Y.; Wang, Y.; Chu, J.; Zhuang, Y.; Zhang, L.; Zhang, S.
    Improved production of erythromycin A by expression of a heterologous gene encoding S-adenosylmethionine synthetase (2007), Appl. Microbiol. Biotechnol., 75, 837-842.
    View publication on PubMed
Search for more literature for 2.5.1.6

Application

Application Comment Organism
synthesis improved production of erythromycin A by expression of a heterologous gene encoding S-adenosylmethionine synthetase in Saccharopolyspora erythraea Streptomyces spectabilis

Cloned(Commentary)

Cloned (Comment) Organism
chromosomal integration and expression in Saccharopolyspora erythraea strain E2 resulting in the overexpressing strain E1, subcloning in Escherichia coli strains ET12567 and DH5alpha Streptomyces spectabilis

Protein Variants

Protein Variants Comment Organism
additional information improved production of erythromycin A by expression of MAT in Saccharopolyspora erythraea E1 Streptomyces spectabilis

Localization

Localization Comment Organism GeneOntology No. Textmining

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Streptomyces spectabilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-methionine + H2O Streptomyces spectabilis
-
 phosphate + diphosphate + S-adenosyl-L-methionine
-
 ?

Organism

Organism UniProt Comment Textmining
Streptomyces spectabilis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-methionine + H2O
-
 Streptomyces spectabilis phosphate + diphosphate + S-adenosyl-L-methionine
-
 ?

Synonyms

Synonyms Comment Organism
MAT
-
 Streptomyces spectabilis
S-adenosylmethionine synthetase
-
 Streptomyces spectabilis

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Streptomyces spectabilis