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Literature summary for 2.5.1.6 extracted from
- Partial purification and characterization of tumor and liver S-adenosylmethionine synthetases (1977), Cancer Res., 37, 427-435.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| SH-reagents | liver enzyme: requirement, tumor enzyme: no requirement | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | two isofunctional forms with different Km values | Rattus norvegicus | - |
| Novikoff ascites tumor cell | a single form of enzyme | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2'-deoxy-ATP + L-methionine + H2O | - |
Rattus norvegicus | ? | - |
? |  |
| 3'-deoxy-ATP + L-methionine + H2O | - |
Rattus norvegicus | ? | - |
? | |
| ATP + L-methionine + H2O | - |
Rattus norvegicus | S-adenosyl-L-methionine + phosphate + diphosphate | - |
? | |
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