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Literature summary for 2.5.1.54 extracted from

  • Williamson, R.M.; Pietersma, A.L.; Jameson, G.B.; Parker, E.J.
    Stereospecific deuteration of 2-deoxyerythrose 4-phosphate using 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (2005), Bioorg. Med. Chem. Lett., 15, 2339-2342.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.021
-
D-erythrose 4-phosphate pH 6.8 Escherichia coli
0.65
-
(3S)-2-deoxyerythrose 4-phosphate pH 6.8 Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ 0.06 mM, required Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoenolpyruvate + (3S)-2-deoxyerythrose 4-phosphate + H2O
-
Escherichia coli (5S)-[5H]-3,5-dideoxy-D-arabinoheptulosonate 7-phosphate + phosphate
-
ir
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
-
Escherichia coli 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
ir

Synonyms

Synonyms Comment Organism
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase
-
Escherichia coli
DAH7P synthase
-
Escherichia coli

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.233
-
(3S)-2-deoxyerythrose 4-phosphate pH 6.8 Escherichia coli
1.183
-
D-erythrose 4-phosphate pH 6.8 Escherichia coli
6.08
-
D-erythrose 4-phosphate pH 6.8 Escherichia coli