Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.5.1.54 extracted from

  • Flores, N.; Xiao, J.; Berry, A.; Bolivar, F.; Valle, F.
    Pathway engineering for the production of aromatic compouds in Escherichia coli (1996), Nat. Biotechnol., 14, 620-623.
    View publication on PubMed

Application

Application Comment Organism
biotechnology increased production of aromatic amino acids in E. coli mutants with modified phosphoenolpyruvate metabolism and enhanced transketolase activity Escherichia coli
biotechnology E. coli strains, overproducing the enzyme, excrete it to the medium, which can also be used as a bioindicator for enhanced carbon commitment into the pathway Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O Escherichia coli first enzyme of the aromatic amino acid biosynthesis 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
-
Escherichia coli 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O first enzyme of the aromatic amino acid biosynthesis Escherichia coli 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?