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Literature summary for 2.5.1.54 extracted from

  • Keith, B.; Dong, X.; Ausubel, F.M.; Fink, G.R.
    Differential induction of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase genes in Arabidopsis thaliana by wounding and pathogenic attack (1991), Proc. Natl. Acad. Sci. USA, 88, 8821-8825.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information DHS1 is induced 3-5fold by wounding of the leaf and pathogen attack Arabidopsis thaliana

Cloned(Commentary)

Cloned (Comment) Organism
DHS1 and DHS2, complementation of Saccharomyces cerevisiae mutant strain YBK7 Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast DHS1 and DHS2 Arabidopsis thaliana 9507
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additional information presence of amino-terminal extension characteristic of chloroplast transit peptides on DSH1 and DSH2 suggests that both proteins may be targeted to the chloroplast Arabidopsis thaliana
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O Solanum tuberosum
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2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O Arabidopsis thaliana DSH1 RNA levels increase in Arabidopsis leaves subjected either to physical wounding or to infiltration with pathogenic Pseudomonas syringae strains, DSH2 RNA levels are not increased by these treatments 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
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enzyme is encoded by duplicated genes : DHS1 and DHS2
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Solanum tuberosum
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-
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Source Tissue

Source Tissue Comment Organism Textmining
leaf DHS1 and DHS2 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
-
Solanum tuberosum 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
-
Arabidopsis thaliana 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O DSH1 RNA levels increase in Arabidopsis leaves subjected either to physical wounding or to infiltration with pathogenic Pseudomonas syringae strains, DSH2 RNA levels are not increased by these treatments Arabidopsis thaliana 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?