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Literature summary for 2.5.1.54 extracted from

  • Ganson, R.J.; Jensen, R.A.
    The essential role of cobalt in the inhibition of the cytosolic isoenzyme of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Nicotiana silvestris by glyphosate (1988), Arch. Biochem. Biophys., 260, 85-93.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
N-[Phosphomonomethyl]glycine concentration of Co2+ markedly increases the concentration of N-[phosphomonomethyl]glycine required for inhibition; cytosolic isozyme; i.e. glyphosate Nicotiana sylvestris

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol isozyme Nicotiana sylvestris 5829
-

Organism

Organism UniProt Comment Textmining
Nicotiana sylvestris
-
cytosolic isozyme
-

Purification (Commentary)

Purification (Comment) Organism
partial Nicotiana sylvestris

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
-
Nicotiana sylvestris 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Nicotiana sylvestris

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.6
-
assay at Nicotiana sylvestris