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Literature summary for 2.5.1.30 extracted from

  • Zhang, Y.W.; Koyama, T.; Ogura, K.
    Two cistrons of the gerC operon of Bacillus subtilis encode the two subunits of heptaprenyl diphosphate synthase (1997), J. Bacteriol., 179, 1417-1419.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
29122
-
1 * 29122 (GerC1) + 1 * 39516 (GerC3), GerC3 supplies the sites for the substrate binding and catalytic activity of HepPP synthase, GerC1 plays an auxiliary but essential role in enzymatic catalysis, calculated from sequence Bacillus subtilis
39516
-
1 * 29122 (GerC1) + 1 * 39516 (GerC3), GerC3 supplies the sites for the substrate binding and catalytic activity of HepPP synthase, GerC1 plays an auxiliary but essential role in enzymatic catalysis, calculated from sequence Bacillus subtilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate Bacillus subtilis heptaprenyl diphosphate synthase is involved in the biosynthesis of the side chain of menaquinone-7 4 diphosphate + all-trans-heptaprenyl diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Bacillus subtilis P31112 and P31114 P31112: subunit 1 (gerC1), P31114: subunit 2 (gerC3)
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate
-
Bacillus subtilis 4 diphosphate + all-trans-heptaprenyl diphosphate
-
?
(2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate heptaprenyl diphosphate synthase is involved in the biosynthesis of the side chain of menaquinone-7 Bacillus subtilis 4 diphosphate + all-trans-heptaprenyl diphosphate
-
?

Subunits

Subunits Comment Organism
heterodimer 1 * 29122 (GerC1) + 1 * 39516 (GerC3), GerC3 supplies the sites for the substrate binding and catalytic activity of HepPP synthase, GerC1 plays an auxiliary but essential role in enzymatic catalysis, calculated from sequence Bacillus subtilis

Synonyms

Synonyms Comment Organism
HepPP synthase
-
Bacillus subtilis

General Information

General Information Comment Organism
physiological function heptaprenyl diphosphate synthase is involved in the biosynthesis of the side chain of menaquinone-7 Bacillus subtilis