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Literature summary for 2.5.1.29 extracted from

  • Thabet, I.; Gregory Guirimand, G.; Guihur, A.; Lanoue, A.; Courdavault, V.; Papon, N.; Bouzid, S.; Giglioli-Guivarch, N.; Simkin, A.; Clastre, M.
    Characterization and subcellular localization of geranylgeranyl diphosphate synthase from Catharanthus roseus (2012), Mol. Biol. Rep., 39, 3235-3243.
    View publication on PubMed
Search for more literature for 2.5.1.29

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis, expression in Escherichia coli strain BL21(DE3), functional complementation of the carotenogenic crt gene cluster in Escherichia coli, YFP-tagged GGPPS expression in Catharanthus roseus cell culture Catharanthus roseus

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast the type II GGPS carries an N-terminal transit peptide allowing plastid import and stroma/stromules localization of the protein Catharanthus roseus 9507
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Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
41600
-
 x * 41600, about, sequence calculation Catharanthus roseus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate Catharanthus roseus
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 diphosphate + geranylgeranyl diphosphate
-
 ?
additional information Catharanthus roseus the enzyme geranylgeranyl diphosphate synthase from Catharanthus roseus catalyses the formation of geranylgeranyl diphosphate from isopentenyl diphosphate and dimethylallyl diphosphate via three successive condensation reactions, exhibiting the activities of EC 2.5.1.1, EC 2.5.1.10, and EC 2.5.1.29 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Catharanthus roseus Q42698
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-

Source Tissue

Source Tissue Comment Organism Textmining
cell suspension culture cell line C20D Catharanthus roseus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate
-
 Catharanthus roseus diphosphate + geranylgeranyl diphosphate
-
 ?
additional information the enzyme geranylgeranyl diphosphate synthase from Catharanthus roseus catalyses the formation of geranylgeranyl diphosphate from isopentenyl diphosphate and dimethylallyl diphosphate via three successive condensation reactions, exhibiting the activities of EC 2.5.1.1, EC 2.5.1.10, and EC 2.5.1.29 Catharanthus roseus ?
-
 ?

Subunits

Subunits Comment Organism
? x * 41600, about, sequence calculation Catharanthus roseus

General Information

General Information Comment Organism
evolution the enzyme from Catharanthus roseus is a plant type II GGPS belonging to the short-chain prenyltransferase subfamily Catharanthus roseus
metabolism the enzyme geranylgeranyl diphosphate synthase from Catharanthus roseus catalyses the formation of geranylgeranyl diphosphate from isopentenyl diphosphate and dimethylallyl diphosphate via three successive condensation reactions, exhibiting the activities of EC 2.5.1.1, EC 2.5.1.10, and EC 2.5.1.29 Catharanthus roseus