Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.5.1.29 extracted from

  • Fujiwara, S.; Yamanaka, A.; Hirooka, K.; Kobayashi, A.; Imanaka, T.; Fukusaki, E.
    Temperature-dependent modulation of farnesyl diphosphate/geranylgeranyl diphosphate synthase from hyperthermophilic archaea (2004), Biochem. Biophys. Res. Commun., 325, 1066-1074.
    View publication on PubMed
Search for more literature for 2.5.1.29

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Thermococcus kodakarensis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0017
-
 farnesyl diphosphate pH 8.0, 70°C Thermococcus kodakarensis
0.0022
-
 geranyl diphosphate pH 8.0, 70°C Thermococcus kodakarensis
0.0094
-
 farnesyl diphosphate pH 8.0, 90°C Thermococcus kodakarensis
0.0095
-
 dimethylallyl diphosphate pH 8.0, 70°C Thermococcus kodakarensis
0.022
-
 geranyl diphosphate pH 8.0, 90°C Thermococcus kodakarensis
0.023
-
 dimethylallyl diphosphate pH 8.0, 90°C Thermococcus kodakarensis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38326
-
 2 * 38326, calculation from nucleotide sequence Thermococcus kodakarensis
85000
-
 gel filtration Thermococcus kodakarensis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(E,E)-farnesyl diphosphate + isopentenyl diphosphate Thermococcus kodakarensis bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature. The enzyme contributes to adjust the membrane composition to the cell growth temperature modulating its substrate and product specificities geranylgeranyl diphosphate + diphosphate
-
 ?
geranyl diphosphate + isopentenyl diphosphate Thermococcus kodakarensis bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature. The enzyme contributes to adjust the membrane composition to the cell growth temperature modulating its substrate and product specificities diphosphate + trans,trans-farnesyl diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Thermococcus kodakarensis Q76CZ2
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Thermococcus kodakarensis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(E,E)-farnesyl diphosphate + isopentenyl diphosphate bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature. The enzyme contributes to adjust the membrane composition to the cell growth temperature modulating its substrate and product specificities Thermococcus kodakarensis geranylgeranyl diphosphate + diphosphate
-
 ?
(E,E)-farnesyl diphosphate + isopentenyl diphosphate bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature Thermococcus kodakarensis geranylgeranyl diphosphate + diphosphate
-
 ?
dimethylallyl diphosphate + isopentenyl diphosphate bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature Thermococcus kodakarensis ? + diphosphate
-
 ?
geranyl diphosphate + isopentenyl diphosphate bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature. The enzyme contributes to adjust the membrane composition to the cell growth temperature modulating its substrate and product specificities Thermococcus kodakarensis diphosphate + trans,trans-farnesyl diphosphate
-
 ?
geranyl diphosphate + isopentenyl diphosphate bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature Thermococcus kodakarensis diphosphate + trans,trans-farnesyl diphosphate
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 38326, calculation from nucleotide sequence Thermococcus kodakarensis

Synonyms

Synonyms Comment Organism
farnesyl diphosphate/geranylgeranyl diphosphate synthase bifunctional enzyme EC2.5.1.29/EC2.5.1.10 Thermococcus kodakarensis
Tk-IdsA
-
 Thermococcus kodakarensis
trans-prenyl diphosphate synthase
-
 Thermococcus kodakarensis