Inhibitors | Comment | Organism | Structure |
---|---|---|---|
diphosphate | 10 mM, more than 90% inhibition | Sus scrofa | |
farnesyl diphosphate | above 0.025 mM | Sus scrofa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | activates, less effective than Mg2+ | Sus scrofa | |
Mg2+ | required for activity | Sus scrofa | |
Mg2+ | less effective than Mn2+ | Sus scrofa | |
Mn2+ | required for activity | Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
300000 | - |
gel filtration | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(E,E)-farnesyl diphosphate + isopentenyl diphosphate | Sus scrofa | no activity with dimethylallyl diphosphate | geranylgeranyl diphosphate + diphosphate | - |
? | |
geranyl diphosphate + 2 isopentenyl diphosphate | Sus scrofa | - |
geranylgeranyl diphosphate + 2 diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
ammonium sulfate, DEAE Sephadex a-50, hydroxylapatite | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0000279 | - |
- |
Sus scrofa |
Storage Stability | Organism |
---|---|
-20°C, at least 1 month, no loss of activity | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(E,E)-farnesyl diphosphate + isopentenyl diphosphate | no activity with dimethylallyl diphosphate | Sus scrofa | geranylgeranyl diphosphate + diphosphate | - |
? | |
geranyl diphosphate + 2 isopentenyl diphosphate | - |
Sus scrofa | geranylgeranyl diphosphate + 2 diphosphate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
- |
Sus scrofa |