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Literature summary for 2.5.1.22 extracted from
- Kinetic properties of spermine synthase from bovine brain (1983), Biochem. J., 215, 669-676.
General Stability
| General Stability | Organism |
|---|---|
| bovine serum albumin stabilizes enzyme in dilute solutions | Bos taurus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5'-methylthioadenosine | kinetics | Bos taurus |  |
| additional information | not inhibitory: decarboxylated adenosylmethionine | Bos taurus | |
| spermine | kinetics | Bos taurus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0001 | - |
S-adenosylmethioninamine | - |
Bos taurus | |
| 0.006 | - |
spermidine | - |
Bos taurus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Bos taurus | 5829 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = S-methyl-5'-thioadenosine + spermine | mechanism | Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosylmethioninamine + spermidine | - |
Bos taurus | 5'-methylthioadenosine + spermine | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
- |
Bos taurus |
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Release 2023.1 (January 2023)
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