Literature summary for 2.5.1.21 extracted from

Pattanaik, B.; Englund, E.; Nolte, N.; Lindberg, P.
Introduction of a green algal squalene synthase enhances squalene accumulation in a strain of Synechocystis sp. PCC 6803 (2020), Metab. Eng. Commun., 10, e00125 .

Search for more literature for 2.5.1.21

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Synechocystis sp. PCC 6803	Botryococcus braunii
heterologous expression of a squalene synthase from Botryocuccus braunii can increase squalene accumulation in a DELTAshc strain of Synechocystis	Botryococcus braunii

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Ni2+	the enzyme is induced by the addition of 0.0025 mM Ni2+	Botryococcus braunii

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2 farnesyl diphosphate + NADPH + H+	Botryococcus braunii	-	squalene + 2 diphosphate + NADP+	-	?

Organism

Organism	UniProt	Comment	Textmining
Botryococcus braunii	Q9SDW9	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2 farnesyl diphosphate + NADPH + H+	-	Botryococcus braunii	squalene + 2 diphosphate + NADP+	-	?

Subunits

Subunits	Comment	Organism
?	x * 45000, FLAG-tagged enzyme, SDS-PAGE	Botryococcus braunii

Synonyms

Synonyms	Comment	Organism
BSS	-	Botryococcus braunii

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Botryococcus braunii

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Release 2023.1 (January 2023)