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Literature summary for 2.5.1.21 extracted from

  • Shechter, I.; Bloch, K.
    Solubilization and purification of trans-farnesyl pyrophosphate-squalene synthetase (1971), J. Biol. Chem., 246, 7690-7696.
    View publication on PubMed

General Stability

General Stability Organism
markedly stabilized by 30% glycerol and 0.02 M 2-mercaptoethanol Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information
-
Saccharomyces cerevisiae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
42600
-
sucrose density gradient centrifugation, gel filtration Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
farnesyl diphosphate + NAD(P)H
-
Saccharomyces cerevisiae squalene + diphosphate + NAD(P)+
-
?

Cofactor

Cofactor Comment Organism Structure
NADH
-
Saccharomyces cerevisiae
NADPH
-
Saccharomyces cerevisiae