Inhibitors | Comment | Organism | Structure |
---|---|---|---|
S-(2,4-dinitrophenyl)glutathione | mixed-type inhibition by reaction product, complex inhibition pattern | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | single turnover stopped flow kinetics and equilibrium dialysis analysis of GSH biniding affinity and stoichiometry, dissociation constants, overview | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | associated, MGST1 | Rattus norvegicus | 16020 | - |
microsome | - |
Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male sprague-dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + 1-chloro-2,4-dinitrobenzene | - |
Rattus norvegicus | S-(2,4-dinitrophenyl)glutathione + HCl | - |
? | |
additional information | MGST1 possesses glutathione transferase and peroxidase activity. Native MGST1 binds three GSH molecules per trimer but with different affinities for GSH, it possesses only one high affinity catalytically competent site per trimer, nanoelectrospray mass spectrometric analysis, overview | Rattus norvegicus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
trimer | native MGST1 binds three GSH molecules per trimer but with different affinities for GSH, it possesses only one high affinity catalytically competent site per trimer, nanoelectrospray mass spectrometric analysis, overview | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
MGST1 | - |
Rattus norvegicus |
microsomal glutathione transferase 1 | - |
Rattus norvegicus |
More | MGST1 that belongs to the membrane associated proteins in eicosanoid and glutathione metabolism, MAPEG, superfamily | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
assay at | Rattus norvegicus |